MR Spectroscopy of Premature Newborns
نویسندگان
چکیده
Introduction MRI techniques have recently demonstrated the ability to provide valuable anatomic imaging in the newborn brain, but additional metabolic markers would be important to provide improved assessments of neonatal brain injury. 3D point-resolved spectroscopic imaging (PRESS-MRSI) can provide accurate measurements of metabolite levels throughout the brain, but it is more complex than commercially available single voxel and 2D MRSI techniques. In this study, lactate-edited 3D-PRESS was used to acquire MRSI in neonatal subjects, in order to better define the extent of normal and abnormal metabolite distributions. This study of 55 premature neonates (many studied serially for a total of 104 exams) demonstrated significant correlation between age and metabolite ratios.
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